Thursday, August 28, 2008

Insightful Government Solutions

For over 18 years Insightful has been providing government agencies with rigorous analytical solutions, helping to increase efficiencies, discover trends and reduce spending. Virtually every major branch of the US federal government uses Insightful technology for data analysis including, the Centers for Disease Control, the National Institutes of Health, the Department of Defense, the Federal Reserve Board, the Federal Drug Administration, NASA, intelligence agencies, and the IRS. Our products allow agencies to turn statistical analysis into actionable decisions, helping decision makers deliver results.

The Insightful Product Family Includes:

* S-PLUS®: platform for data analysis and visualization
* Insightful Miner™: desktop data mining workbench
* S-PLUS Server: platform for web and distributed data analysis applications

Statistical analysis software

Insightful Academic Solutions

Insightful Corporation offers a range of statistical data analysis and data mining products for administrators, faculty members, institutional researchers and students. We offer competitive pricing and a range of licensing options to help you easily integrate our products into curricula for research, graduate and undergraduate uses.

As a faculty member, you can feel confident that our statistical data analysis and data mining products offer your students the opportunity to use software that leading analysts employ to solve mission-critical business problems at Global 1000 companies. Insightful's easy-to-use Insightful Miner and S-PLUS product lines make it easy for students to access, analyze and report findings professionally to their peers and faculty members.

For institutional researchers, S-PLUS and Insightful Miner provide a scalable data analysis workbench that provides the flexibility and extensibility you need to access, analyze, visualize and report your discoveries to colleagues and the broader academic and research communities.
For graduating students, we offer heavily discounted pricing and licensing options for those starting their careers.

As an administrator, use our exploratory data analysis and data mining solutions to improve intelligence gathering from your data to improve student retention and graduation dates. Access, analyze and report important discoveries about student data, build predictive models to determine which alumni are most likely to contribute to your organization and improve your ability to forecast your organizational needs and resource demands.

Helpful Links

*S-PLUS e-Academy: Discover for yourself the data analysis tool preferred by industry leaders worldwide. As a university student, you are eligible for a FREE copy of S-PLUS Student Edition.
*User Stories
* Resources
*Demos and Downloads
*Latest Product Information

* Format to cite S-PLUS® in documentation:
S-PLUS® (version #), c (year), Insightful Corporation, Seattle, WA http://www.insightful.com

Statistical analysis software

Telecommunications Solutions

From Internet, telephone and cable services to voice and electronic mail, telecommunications services touch our lives every day. In this fast-growing, competitive, price-sensitive industry, firms such as Verizon must continually evaluate and improve the performance of their programs and services to stay ahead of the competition. Insightful software provides the predictive modeling capabilities required to understand customer preferences, predict system performance and report on network operations.

Key Applications:

* Business Performance Reporting
* Reduce Customer Churn
* Fraud Detection
* Data Quality Management
* Marketing Campaign Analysis
* Customer Behavior Modeling

"With Insightful's visualization capabilities, the company [AT&T] has reduced the time required to assess system issues from a day to 30 minutes. Now engineers spend less time trying to uncover what the service issue may be and can spend more time addressing quality of service issues"

Doug Baranek
Engineer
AT&T

Statistical analysis software

Insightful Manufacturing Solutions

Leaders as diverse as Motorola, Intersil and General Mills rely on Insightful to uncover a product's critical design factors, such as which variables have the biggest impact on performance, what are the best possible settings or proportions and what are the most favorable operating conditions. Insightful provides solutions for experimental design and analysis, reliability analysis and life expectancy testing, business performance reporting and demand forecasting and optimization.

Key Applications:

* Design and Analysis of Experiments
* Reliability Analysis and Life Expectancy
* Field Failure Analysis and Reporting
* Supply Chain Optimization
* Demand Forecasting, Optimization and Reporting
* Statistical Process Control/Six Sigma

"We selected S-PLUS because it offered superior visualization tools and could provide information-rich, one-page analytic reports. Further, the software offers a flexible programming language for prototyping new analytics quickly to meet changing conditions. High-performance analytics and superior visualization capabilities make it an indispensable part of our organization and improves productivity."

Dr. Phillip Stafford
Sr. Scientist
Motorola Life Sciences

User Stories

* Macronix Deploys S-PLUS Enterprise Server to Reduce Defects and Improve Yield for Wafer Fabrication
* Dr. Bill Meeker of Iowa State University awarded Chicago ASA Statistician of the Year. Download his presentation from the 2005 Insightful User Conference "Using Simulation and Graphics as an Aid in Planning Complicated Experiments "
* Pillsbury Deploys Innovative Data Analysis Tool Kit
* S-PLUS® Improves Productivity and Quality of Kraft Products
* Motorola Life Sciences Selects to Manufacture High-quality Biochips

Statistical analysis software

Marketing Optimization

Determine Optimal Marketing Triggers at the Customer Level

Successful marketing is about increasing efficiency and decreasing time to market. With Insightful’s Marketing Optimization solution you can:incorporate predictive analytics and reporting into your campaign planning process. This will allow your organization to realize a substantial return on investment through increases in qualified response rates, offer acceptance, customer retention and campaign profitability.

* Easily define segments, obtain fast counts, and create a library list using workflow tools
* Create ‘what-ifs’ scenarios to assist in campaign planning, forecasting results based on variable assumptions and costs
* Optimize multiple campaigns via multiple users, deployed via multiple channels and with the ability to support multi-step, event driven/trigger based and recurring/automated activity
* Segment for more targeted higher impact campaigns.
* Target high value prospects and customers
* Focus on metrics like profitability instead of just response
* Analyze promotion history, report and store promotion effectiveness and integrate with multi-dimensional tools

The Insightful Marketing Optimization solution provides robust and streamlined model building and deployment for non-statisticians. This capability enables organizations to develop sophisticated and highly effective marketing programs based on predictive modeling techniques without the need to hire statisticians.

Statistical analysis software

Customer Win-Back

Bring Your Best Customers Back

When good customers go away, you work to get them back. With predictive analytics you can make your marketing dollar work smarter so reactivating customers is a profitable activity, adding to your bottom line with the first new purchase. With Insightful’s Customer Reactivation solution you can:

* Calculate new potential Lifetime Value (LTV) of candidates
* Target high value lost customers
* Model focused campaigns for the highest return

With your historical data matched to present day conditions Insightful’s solution will refine your marketing efforts. Analysis and modeling will help you to target likely candidates for win-back and create compelling offers.

Statistical analysis software

Customer Retention

Recognize Churn Triggers and Implement Programs to Retain Your Best Customers

You, as a marketing professional, know it costs more to acquire a new customer than to keep one. You also know that keeping customers happy and profitable can be hard to do. You need to identify and anticipate the triggers that are signaling you a customer is about to leave or become inactive. With Insightful’s Customer Retention solution you can:

* Predict which customers have the highest propensity to churn
* Identify and understand behaviors that lead to churn
* Increase customer loyalty
* Retain high value customers

Our Customer Retention solution can help you work proactively to keep your most desirable customers, and keep them satisfied. Ultimately, you will notice substantial decrease in customer churn rates, while increasing profitability and loyalty.

Statistical analysis software

Monday, August 25, 2008

Customer Growth

Grow Each of your Customer Relationships to Maximize Lifetime Value (LTV)

Acquiring new customers requires the majority of a marketing organization’s budget, time and focus. Yet, acquisition is only the beginning of the relationship. If you understand the potential Lifetime Value (LTV) of your customers, you can accelerate profitability and maximize the return on the marketing spend. With Insightful’s Customer Growth solution you can:

* Understand and predict your customers' LTV
* Grow marketing ROI through campaign optimization
* Cross-sell the most appropriate products at the right time and through the right channel
* Increase customer wallet-share
* Improve the success rate selling new products to current customers

Understanding Customer Lifetime Value ensures your total marketing investment assists in deepening customer relationships and increasing profitability. Through the use of predictive analytics you can create offers and campaigns that appeal directly to your most profitable customers, gaining a greater share of their discretionary spend. You can further analyze campaign results to create new offers and campaigns that keep your company top-of-mind and increase overall customer value.

Statistical analysis software

Customer Acquisition

Target and Sell to the Right Prospect, Right Now

Acquiring new customers creates distinct challenges for marketing organizations. How do you deliver the right message to the right prospect through the right channel at the right time? How do you ensure only sales ready leads are moved into the sales pipeline and the rest are cultivated?

Intense competition for new customers can substantially increase the cost per lead while decreasing potential customer lifetime value. Through the use of predictive analytics, marketing professionals can continually optimize marketing campaigns to ensure profitable results.

Insightful’s Customer Acquisition solution will help you to:

* Create profiles of optimal prospects
* Target likely prospects to become high value customers
* Increase offer effectiveness and profitability
* Deliver more and better qualified leads to sales
* Assess and analyze results for use in future campaigns
* Segment prospects to optimize messages, products, and offers

According to Gartner 70% of inquiries generated by marketing are never acted on because they do not reach the right person or organization at the right time. Acquiring new customers is a costly endeavor. With Insightful’s Customer Acquisition solution you can minimize your costs; effectively targeting prospects with optimized offers to drive a higher return on your marketing dollar.

Statistical analysis software

Marketing Analytics Solutions

Realize a Higher Marketing ROI with Predictive Analytics

Marketing as usual is no longer an option. Prospects and customers are overwhelmed by thousands of competing messages, resulting in information overload. As a marketing professional it is your job to cut through the noise with the right offer, to the right person, with the right channel at the right time. By better targeting and segmenting prospects and customers your organization can:

* Cultivate more sales ready prospects
* Grow profitable customer relationships
* Improve customer intelligence and behavioral data
* Increase customer loyalty
* Optimize marketing campaign performance
* Maximize your marketing ROI

Insightful’s Marketing Analytics solutions put the power of predictive analytics to work for you to create more targeted, effective campaigns. Our solutions will help you to develop insight into customer lifetime value and customer preferences and affinity towards offers. Insightful solutions deliver customer behavior models and marketing optimization models for:

* Customer Acquisition
* Customer Growth
* Customer Retention
* Customer Win-Back
* Marketing Optimization



Whether you are looking to increase your sales pipeline with more qualified leads, grow customer lifetime value or increase the retention rate of high value customers, Insightful’s Marketing Analytics solutions will deliver the results that you need to ensure your organization's success.

Statistical analysis software

Optimized Portfolio Management

With Insightful’s innovative optimized portfolio management solution, you can streamline the portfolio construction, optimization, and backtesting functions, while delivering superior risk-adjusted returns on either client portfolios or internal treasury portfolios.

Insightful’s Optimized Portfolio Management solution provides a statistically rigorous software framework to optimize a financial portfolio, using techniques ranging from the classic mean-variance approach to more complex objective functions involving logarithmic returns and coherent risk measures such as expected shortfall.

* Achieve competitive advantage by seamlessly integrating the portfolio construction, testing, and optimization, and reporting workflow

* Rapidly prototype and test out portfolio models

* Handle large number of asset types

* Free up quants from redundant tasks - such as re-running analysis with a different date range, different set of inputs – to develop new models, develop trading strategies, and more value-added tasks

* Replace spreadsheets with a workflow solution that is scalable and allows collaboration

* Flexibly and rapidly implement multiple models using different risk-return objectives

The Optimized Portfolio Management solution from Insightful can help your organization gain an edge by providing advanced optimization techniques, a scalable statistical and financial function library that let’s you analyze and study time-series data, backtest your portfolios, and generate a variety of performance reports.

Statistical analysis software

Risk Management Framework

Risk arises from uncertainties surrounding your business operations and environment. Not understanding these uncertainties can result in unexpected losses to your firm and others in your value-chain. How you measure uncertainty and account for it within your operations impacts new product development and pricing, the calculation of capital allocation, and can directly influence institutional performance in volatile markets with unexpected external events.

Insightful’s Risk Management Framework is a software and services solution that will provide you with a rigorous modeling framework and state of the art models for credit risk, market risk and operational risk measurement and calculation. With the Risk Modeling Framework from Insightful in place, your institution can:

* Avoid losses from unexpected credit quality deterioration

* Deliver more effective hedging against market fluctuations

* Improve the alignment of your capital allocation with your institution’s true, economic risk

* Improve your RAROC and RORAC ratings

* Increase your net interest margin

Protect your organization from unnecessary risk, while working to ensure the risks you take positively impact profit and shareholder value. Leverage your existing risk management infrastructure, reduce the possibility of operational disruption, safeguard against insolvency and lower your overall cost of capital.

Our Risk Management Framework:

* Provides a scalable risk modeling platform that facilitates collaboration, what-if scenario testing, and allows you to test out hypotheses around loss distributions
* Provides the ability to fit data to distributions and/or create simulated data
* Provides a robust framework to back-test your models, and stress them with realistic and extreme scenarios

Statistical analysis software

Regulatory Compliance

Solvency II

More than just meeting the requirements laid down by Solvency II, organizations can benefit from sound process oriented capital management practices. Achieving compliance can lead to better credit ratings, increased shareholder value and improved business metrics such as:

* Volatility of P&L
* Volatility of Earnings
* RAROC™
* RORAC

Insightful’s regulatory compliance solution for Solvency II provides a rigorous statistical framework of software and consulting services that allows you to model all material risks, quantify them, derive the correlations across multiple lines of businesses, and implement both advanced internal models and the prescriptive standard formula to determine solvency levels. Our solution allows your organization to comprehensively document and accurately perform and report:

* Calibration test results
* Statistical test results
o Backtesting
o Stress testing, and
o Model validation
* Identify & model all risk mitigation structures
* Capital Requirement calculations based upon aggregated risk distributions
* Internal Model-Based Capital Requirements vs. Standard Model comparison and reporting
* SCR (using both the Standard Formula and through the use of Internal Models), and MCR

Align your regulatory capital requirements with your true economic risk and realize savings by lowering your total cost of capital. With Insightful’s regulatory compliance solution for Solvency II, your organization can gain approval from the national supervisor, lower your earnings volatility and improve overall shareholder value.

Statistical analysis software

Enterprise Risk Aggregation

Is your organization comprehensively managing risk? Or like so many financial services institutions, are you struggling with isolated and or restricted views that create sub-optimal business investment decisions; driving up the cost of your capital and the overall exposure of your institution?

Insightful’s Enterprise Risk Aggregation solution provides a statistically rigorous software framework that aggregates your correlated risk across business units, geographies and product types. You can move your team beyond just meeting economic capital requirements to leveraging a platform that facilitates true business decision support through an enterprise level view into your institution’s risk.

* Reduce variability in both quantitative and qualitative measures of performance

* Optimize your economic capital allocation

* Improve your capability to predict loss and return on enterprise risk

* Improve credit rating and lower your reputation risk

* Lower your overall cost of capital in the marketplace



The Enterprise Risk Aggregation solution from Insightful can help your organization to protect shareholder value through a more efficient and cost-effective use of capital while maintaining a sufficient cushion against unexpected losses. Your team can proactively model M&A opportunities, meet regulatory compliance reporting requirements and create the edge you need to compete and win in this demanding and volatile market environment.

Statistical analysis software

Wednesday, August 20, 2008

Insightful Finance Solutions

Insightful finance solutions are specifically designed to meet both your strategic and regulatory needs. Today’s market is experiencing increased competition, more regulation and rising volatility. You need to optimize your capital allocation, lower your overall cost of capital, and improve and/or maintain your favorable credit rating. You are also fighting to maintain regulatory compliance while increasing profits. You need analytic and reporting solutions that are rigorous enough to meet regulatory scrutiny, yet flexible enough to fit the unique requirements of your institution.

* Insightful Enterprise Risk Aggregation
* Insightful Regulatory Compliance
* Insightful Risk Management Framework
* Insightful Portfolio Optimization

Insightful finance solutions are built upon the award-winning analytics platform, S-PLUS®. We have twenty years of continued investment in delivering the best econometrics capabilities, a standards-based IT friendly architecture and superior graphic reporting for the easy distribution and comprehension of your results across all audiences.
For more information, please make your selection from among our white papers, case studies and archived Web casts:

* Archived Events & Web Casts
* Success Stories
* Whitepapers & Application Notes

Statistical analysis software

Clinical Safety Data Analysis

Insightful Safety

Safety data have traditionally been summarized as tables and listings that are difficult to review and interpret. In today’s climate of heightened safety concerns, these formats are inadequate for quick and accurate interpretation and comprehension. Insightful Safety provides methods for the rigorous analysis of safety data. Analysis results and reports can be readily deployed for interactive review and for submission / reporting.

* Quantify treatment effects on safety endpoints
* Identify safety signals quickly and accurately
* Select the best dose in early-phase trials
* Identify patients with lab and/or AE issues early in all trials

Safety data pose many challenges to the analyst; there are many endpoints (labs/analytes and adverse events) and comparisons to make, resulting in a testing multiplicity issue. Further, AE count data are sparse, thus complicating the analysis. Insightful Safety packages include advanced statistical methods such as Bayesian hierarchical models and inside-out machine learning models that directly address the peculiar safety data issues. These methods provide accurate statistical inference and rapid identification of safety signals.


pRisk plot from hierarchical Bayes analysis of adverse event rates

Improve analysis of safety data and identify safety issues faster

* Rigorous statistical analysis of safety data
* Advanced statistical methods that overcome limitations of traditional methods

Deploy analytic best practices across functional areas

* Reporting of analysis results to safety, epidemiology and clinical study teams
* Deployment of best practices safety analysis throughout organization
* More efficient use of biostatistics resources

Align with regulatory and company mandates

* Analyses supporting periodic and aggregate review of safety data

Statistical analysis software

Clinical Trial Design

Insightful Trial Designer

For innovative clinical trial design, Insightful Trial Designer solution provides intuitive interfaces and easy-to-use workflows for designing, monitoring and simulating flexible clinical trials. The solution will assist you in deploying shorter trials while increasing the probability of their success.

* Point-and-click and S-PLUS® programming interfaces
* Packaged, sequential clinical trial designs
* Custom (e.g. adaptive) designs and outputs
* Validated installation and operation

The Insightful Trial Designer solution is fully integrated with the award winning S-PLUS platform, a validated, industry standard biostatistics programming environment. Our solution allows you to extend your proprietary and standard methods for greater ease of design and testing.


Compute, evaluate and compare clinical trial designs

Reduce Cost and Time of Clinical Trials

* Simulate multiple trials to examine effect on power and type 1 error
* Promote rapid discovery of new beneficial treatments
* Discriminate between relevant scientific hypotheses
* Integrate with your electronic data capture (EDC) methods

Protect Interests of Patients in Trial

* Stop when credible decision can be made
* Stop if unsafe or unethical

Comprehensive Design and Evaluation Tools

* All commonly used group sequential designs, boundary shapes and scales included
* Comprehensive evaluation tools:
- Power, conditional power, sample size distribution, inference at the boundaries, and Bayesian analyses
* Flexible Monitoring Methods:
- Implementation of stopping rules based on error spending functions or constrained boundaries
* Exact p-values, confidence intervals; bias adjusted estimates of treatment effect

Advanced Visualization Tools

* Comprehensive set of specialized plots for study design:
- Power curves, ASN (average sample size) curves, and stopping probabilities
* Trellis graphics for powerful and effective comparison of designs

Comply with Regulatory Agencies’ Guidelines

* FDA ICH-E9

Statistical analysis software

Clinical Data Review

Insightful Clinical Review

The cost of clinical trials continues to increase. Clinicians require rapid and guided access to clinical data for critical decision making, especially to ensure that all safety issues are being identified and communicated. Insightful Clinical Review enables interactive, web-based viewing of clinical data from early and late phase clinical trials. The framework includes summaries from graphical and statistical analyses of adverse events, labs and treatment, with drill down to patient profiles that summarize all available data at the patient level. Insightful Clinical Review utilizes advanced S-PLUS statistical graphics and analytics for efficient communication of clinical information in the trial data:

* Identify safety issues quickly
* Guided data review for clinicians, ensuring best practices
* More and better information exchanged in meetings - internally and with regulatory agencies

Insightful Clinical Review provides a framework and tools for development and rapid deployment of advanced statistical and graphical summaries on-line or in portable file formats. When deployed in conjunction with Insightful Clinical Graphics and Insightful Safety, Insightful Clinical Review assists in providing a comprehensive graphical environment for the examination and communication of your data and results for all phases of your clinical trials in progress.



Select adverse event and/or lab summaries then drill to patient profile. Clinical graphics / statistics menu on left and on-top banner may be configured to customer requirements.

Improve the quality of decisions

* Select the best dose in early-phase trials
* Identify patients with lab and/or AE issues early in all trials
* Identify potential data errors and enable data cleanup
* Discern safety and efficacy signals in all early and late phase trials

Speed the drug development effort

* Comprehensive data display at the fingertips of your entire team
* Real-time review of all trial data
* Interim analysis of safety and efficacy
* Appropriate attrition and advancement of compounds

Enable better interactions with regulatory agencies

* Online and portable trial summary enables in-time support of FDA interaction team for FDA meetings

Statistical analysis software

Clinical Reporting

Insightful Clinical Study Reporting

Clinical pharmacology and pre-clinical toxicology groups are under tremendous pressure to provide accurate and timely reports in support of critical product milestones. In some situations, this can involve the use of disparate systems and manual processes, increasing the risk of error and requiring redundant validation steps. Insightful Clinical Study Reporting eliminates manual processes, providing a point-and-click workflow for standardized reporting on pharmacokinetics, toxicokinetics and pharmacodynamics for a wide collection of studies.

* Eliminate manual QC processes
* Reduce reporting time up to 75%
* Enforce analysis and reporting best practices

Insightful Clinical Study Reporting supports a consistent and automated process from data acquisition through document generation and distribution. There is no cutting-and-pasting or programming required for producing standard reports; and all reports adhere to regulatory requirements including 21 CFR 11 and GxP.




Select study details, report format and output preferences. Report graphs and tables are produced in strict adherence to detailed formatting requirements.

Pre-clinical, Non-clinical, Clinical Studies; Analyses & Reports

Insightful Clinical Study Reporting supports all pre-clinical, non-clinical and clinical study types, as well as required regulatory components.

IND Filing (Pre-Clinical Studies)

* Short-term Toxicity and TK studies (rodents, higher mammals)
* Carcinogenicity studies (transgenic mice)
* CV, CNS studies

Post IND (Non-Clinical Studies)

* Longer-term TK studies (higher mammals)
* Reproductive Toxicology (genotox, placental)
* Carcinogenicity studies
* Biomarker / PD response studies

Post IND (Clinical Studies)

* PK studies – Single ascending dose, Multiple ascending dose, Bioequivalence
* Biomarker / PD response studies
* Exposure / response studies

Statistical analysis software

Statistical Graphics

Insightful Clinical Graphics

For the effective communication of clinical data across functional areas, and in journals, presentations, and regulatory submissions, Insightful Clinical Graphics enables point-and-click creation of advanced graphics and seamless integration with existing exploratory, presentation, and production reporting environments.

* Reduce graphic development time and cost
* Promote more effective communication across all review and reporting groups
* Realize more efficient resource utilization

Unlike other solutions, Insightful Clinical Graphics enables rapid creation of statistical graphics without programming while generating code for production jobs. Your team can create more effective graphs faster and eliminate redundant processes.



Select standard and custom graph types and specify graph elements, creating statistical graphics for use in presentations and publications.



Apply new styles to all elements in a graph by selecting a new Theme.

Speed the analysis and reporting process

* Point-and-click graph specification - no programming required
* Point-and-click graph edit - for publications, presentations and submissions

Improve the quality of scientific and business decisions

* Comprehensive palette of graphs provide clarity for complex data sets
* Comparative graphical analysis on all safety and efficacy data

Identify safety and efficacy signals faster

* Specialized safety/efficacy graph patterns
* Clear analysis and presentation of results

Enable better and faster interactions with regulatory agencies

* Eliminate redundant processes and streamline submissions
* Integration within validated submission environments

Easily integrate with SAS and production reporting environment

* S+Connector™ for SAS® supports seamless integration with production environments
* Programmers can generate S-PLUS graphics from SAS macros with simple call arguments

Statistical analysis software

Insightful Life Science Solutions

Insightful Life Science Solutions support all phases of pre-clinical and clinical development. Our solutions meet the requirements of a validated environment while providing significant gains in productivity and efficiency. Insightful Life Science Solutions deliver the knowledge to act for effective drug development.

The Insightful Life Science Solutions team offers software solutions for:

* Statistical Graphics: Insightful Clinical Graphics
* Clinical Reporting: Insightful Clinical Study Reporting
* Clinical Data Review: Insightful Clinical Review
* Clinical Trial Design: Insightful Trial Designer
* Clinical Safety Data Analysis: Insightful Safety

Statistical analysis software

Monday, August 4, 2008

Insightful Government and Industry Solutions

The imperative to use data efficiently and effectively spans all industries, but the need is particularly acute in research-driven industries such as life sciences and financial services, where the ability to unlock hidden insight and detect subtle relationships can mean the difference between success and failure.

In the pharmaceutical industry, for example, where companies must be able to bring new compounds to market quickly to replace drugs that are nearing the end of their product lifecycle, there is a vital need for advanced statistical tools that speed drug discovery. Financial services organizations face new regulatory mandates to provide statistical estimations of risk. Meanwhile, the increasing reliance on Six Sigma programs has made statistical analysis a critical tool for manufacturers.

By delivering the power of predictive analytics to users across the enterprise, solutions from Insight are enabling companies in a broad range of industries to dramatically improve decision making processes. Find out how companies in life sciences, financial services, energy, telecommunications, manufacturing, and other industries, as well as government organizations and private institutions, are using Insightful technologies to achieve greater success.

Insightful Solutions:

* Life Sciences
* Finance
* Marketing Analytics
* Manufacturing
* Telecommunications
* Academia
* Government

Statistical analysis software

EnvironmentalStats for S-PLUS: Environmental Statistics

A COMPREHENSIVE SOFTWARE PACKAGE FOR ENVIRONMENTAL STATISTICS

The first choice for environmental data analysis. EnvironmentalStats for S-PLUS, an add-on module to S-PLUS, provides a set of powerful yet simple-to-use pull-down menus and functions for performing graphical and statistical analyses of environmental data. The software brings the major environmental statistical methods found in the literature and regulatory guidance documents into one statistical package, along with an extensive hypertext help system that explains what these methods do, how to use these methods, and where to find them in the environmental statistics literature. Also included are numerous built-in data sets from regulatory guidance documents and the environmental statistics literature.

EnvironmentalStats for S-PLUS will be useful to anyone who has to make sense of environmental data, including hydrologists, soil scientists, atmospheric scientists, geochemists, environmental engineers and consultants, hazardous and solid waste site managers, and regulatory agency analysts and enforcement officers. Parts of EnvironmentalStats for S-PLUS incorporate statistical methods that have appeared in the environmental literature but are not commonly found in any statistical software package. Parts of EnvironmentalStats for S-PLUS are specifically aimed at users who are required to collect and analyze environmental monitoring data in order to comply with federal and state Superfund, RCRA, CERCLA, and Subtitle D regulations. All of the functions in EnvironmentalStats for S-PLUS, however, are useful to anyone who needs to analyze environmental data.

Not just for environmental data. By extending the statistical capabilities of S-PLUS, EnvironmentalStats for S-PLUS is also useful to practitioners outside the field. Anyone who uses S-PLUS will find all sorts of useful functions in EnvironmentalStats for S-PLUS, including functions to plot probability and cumulative distribution functions, a standardized set of functions for estimating distribution parameters and quantiles and computing confidence intervals, new functions and methods for Goodness-of-Fit tests (including Shapiro-Wilk), functions to compute prediction and tolerance intervals, functions to estimate and test for trend, functions to easily create power and sample size plots, functions to handle Type I censored data, and functions to perform probabilistic risk assessment. Furthermore, the glossary of statistical terms is a valuable tool to anyone who wishes to use S-PLUS to learn or teach Statistics.

EnvironmentalStats for S-PLUS includes a comprehensive reference manual and detailed documentation. An excellent companion volume (available separately) is Environmental Statistics with S-PLUS.

EnvironmentalStats for S-PLUS includes an easy-to-use graphical user interface, new functionality for computing and plotting power curves, new hypothesis tests, calibration lines and curves, simultaneous prediction intervals, new functionality for censored data, and much more -- see the feature list for more details.

Key Benefits

* Comprehensive statistical methods and accompanying literature found in a single environment improving productivity
* Invaluable tools for study design from an easy-to-use GUI make it easy to become productive quickly
* Documentation, extensive help files and industry-specific examples
* Advanced visualization tools for analyzing and interpreting results
* Ability to program functions to meet unique organizational needs

Product Information

* Demo: EnvironmentalStats for S-PLUS
* Read client testimonials.

Statistical analysis software

FAME S+Connector: Integration Module for S-PLUS and FAME

Spend Less Time Preparing Data and More Time Analyzing It

Insightful and SunGard® bring you a solid and supported integration module for S-PLUS® and FAME®, the FAME® S+Connector™. Now you can dramatically accelerate the process of bringing accurate financial time series data from FAME into the powerful S-PLUS environment for advanced quantitative analysis.

FAME S+Connector can further simplify object identification and retrieval through optional tools, such as SunGard’s PowerData and Excel-based FAME populator.

Point-and-Click for the Best of Both Worlds

With the FAME S+Connector, analysts can dramatically accelerate the process of bringing accurate data from FAME into the powerful S-PLUS environment for advanced quantitative analysis.

SunGard delivers a wealth of managed financial content to FAME, an object oriented database optimized for financial content with time series and cross-sectional capabilities. FAME provides a truly open, nested environment that offers the same functionality on individual user desktops that runs in FAME’s hosted data centers.

S-PLUS gives users point-and-click access to data manipulation, graphing and statistics. S-PLUS provides an easy to use, graphical user interface founded upon its object oriented, award winning S™ language, making it easy to manipulate and integrate financial content from FAME.

Statistical analysis software

S+Wavelets: Wavelet & Signal Series Analysis

ADVANCED SIGNAL AND IMAGE ANALYSIS SOFTWARE

One of the most exciting developments in applied mathematics is now available for widespread application. With S+Wavelets, you can apply wavelet analysis to an extremely broad range of problems involving signal, time series, or image data. Now there's a comprehensive, modern approach to advanced signal and image analysis, time series analysis, statistical signal estimation, and data compression analysis.

The S+Wavelets toolkit provides a powerful new set of analysis tools, created specifically for scientific and technical data. Working together with the award-winning

S-PLUS data analysis environment, S+Wavelets goes well beyond the capabilities of the Fourier transform for many kinds of signals and images. S+Wavelets can be used for many practical applications, including signal processing, medical imaging, time series analysis, pattern recognition, non-linear signal estimation, and data compression. S+Wavelets helps you develop a complete understanding of data using time-frequency displays, multi-resolution analysis, automatic signal estimation/extraction and denoising, and a comprehensive set of exploratory data analysis plots for wavelet decompositions.



Figure1: This screen demonstrates the best wavelet packet analysis of a quadratic chrip signal. The quadratic chirp is in the upper left and wavelet packet quadratic chrip signal components are in the upper right. A best basis selection tree is in the lower left window. The time-frequency plot in the lower right clearly indicates that frequency increases quadratically over time.

Click here for more Wavelets examples.

Key Benefits

* A comprehensive, modern approach to advanced signal and image, time series, statistical signal and data compression analysis.
* Powerful analytics available in flexible, extensible environment of S-PLUS.
* Robust wavelet analysis including discrete wavelet transformations, non-decimated wavelet transforms and more.

Statistical analysis software

S+SpatialStats: Analysis of Spatial Data

S+SpatialStats is the first comprehensive, object-oriented software package for the analysis of spatial data. Providing a whole new set of analysis tools, S+SpatialStats was created specifically for the exploration and modeling of spatially correlated data.

Taking full advantage of the object-oriented methods and modeling language of S-PLUS, S+SpatialStats allows you to analyze data with spatial structure thoroughly and correctly. S+SpatialStats can be used to analyze data arising in technical areas such as environmental, mining and petroleum engineering, natural resources, geography, epidemiology, demography and others where data is sampled spatially.

SpatialStats Resources

* Australian Centre of the Asian Spatial Information and Analysis Network
* National Geodetic Survey
* USGS National Mapping Information
* Maine Office of GIS
* Desert Research Institute
* NYS Spatial Data
* Spatial Odyssey
* Federal Geographic Data Committee
* Rutgers University-- Center for Remote Sensing and Spatial

Statistical analysis software

S+SeqTrial: Clinical Trial Design & Analysis

THE PREMIER PACKAGE FOR THE DESIGN, MONITORING, AND ANALYSIS OF CLINICAL TRIALS

S+SeqTrial is an S-PLUS software library for designing, monitoring, and analyzing clinical trials using group sequential methods. In a classical fixed sample design, the sample size is set in advance of collecting any data. In sequential design, data are monitored throughout the collection, and the data may be analyzed after a block of data is accrued. This is especially beneficial if electronic data capture (EDC) methods are used for data collection.



Group sequential designs are especially important for the design of Phase II and Phase III clinical trials, where ethical considerations such as patient safety and rapid approval of effective treatments are paramount. Indeed, the FDA now recommends group sequential studies in certain cases.

Key Benefits

* Reduced clinical trial costs using group sequential methods
* Improved study design and comprehensive design and evaluation tools
* Flexible monitoring methods
* Advanced visualization tools for analyzing and interpreting results

Statistical analysis software

S+NuOPT: Large-Scale Constrained Optimization

S+NuOPT is a cutting-edge software package capable of solving very large optimization problems. Designed for analysts and decision makers, NUOPT for S-PLUS is used for a wide range of applications including portfolio optimization, nonlinear and robust statistical modeling, and circuit optimization. The full power of the S-PLUS language is integrated with NUOPT. No other package can match this combination of powerful statistics and graphics with large-scale optimization problem solving, including:

* Linear programming
* Mixed integer programming
* Transportation
* Quadratic programming
* Unconstrained nonlinear optimization
* Multi-objective programming

Figure 1: S+NuOPT allows you to explore different portfolio optimization methods and build in features that reflect real-world constraints. The above figure displays optimized weights computed using two different methods. The weights on the left are rebalanced during each time period independently of the weights during the previous time period. The weights on the right are constrained to smoothly evolve from one time period to the next, resulting in a more stable portfolio allocation.

SAMPLE APPLICATIONS

Portfolio Optimization

* Optimize portfolios of assets incorporating a variety of realistic constraints, going well beyond the classical Mean-Variance (Markowitz) formulation.
* Build complex models that combine different classes of assets and subgroups of assets simultaneously.
* Solve problems involving large portfolios efficiently.

Nonlinear and Robust Statistical Modeling

* Apply new penalized and robust regression methods, traditionally only applicable to small data sets, to very large problems.
* Find better parameter estimates for nonparametric models using global fitting
criterion.

Applications of Mixed Integer Programming in Quantitative Finance

* Basket Selection: given an initial portfolio, select basket of trades given that only a maximum number of trades are allowed (along with other turnover constraints).
* Cardinality Constraints (number of names constraints): given the asset universe, portfolio managers often need to limit the total number of holdings (both long and short) in their final portfolio.
* Buy In Threshold Constraints: some assets can only be purchased or sold at certain minimum levels, or overly small holdings or trades may need to be excluded in an optimum portfolio.
* Round Lots: restrictions defining the basic investment unit. For instance, investors are only allowed to make transactions in integer multiples of these round lots.
* Lower Partial Moments Optimization: Instead of using variance as a risk measure, it is sometimes desirable to optimize on downside deviation. The ability to declare and use integer variables makes it easy to formulate the problem elegantly and therefore solve more efficiently.

Statistical analysis software